Fluoride

Fluoride

SCHEMBL8592140

F.O=C1OCc2ccccc21

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.95
MAOB P27338 5/20 0.95
ALDH1A1 P00352 4/20 0.59
KDM4E B2RXH2 2/20 0.59
HPGD P15428 2/20 0.59
TYMS P04818 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2C19 P33261 1/20 0.59
HSD17B10 Q99714 1/20 0.59
MAPT P10636 4/20 0.53
LMNA P02545 2/20 0.53
GAA P10253 2/20 0.53
RAB9A P51151 2/20 0.49
RECQL P46063 1/20 0.47
PRF1 P14222 1/20 0.47
NPC1 O15118 1/20 0.45
ALOX12 P18054 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CES1 P23141 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22284 0.98 MAOA (1.00) MAOAMAOBALDH1A1KDM4EHPGD
SCHEMBL11522370 0.98 MAOA (1.00) MAOAMAOBALDH1A1KDM4EHPGD
SCHEMBL6903786 0.98 MAOA (1.00) MAOAMAOBALDH1A1KDM4EHPGD
SCHEMBL29448271 0.98 MAOA (1.00) MAOAMAOBALDH1A1KDM4EHPGD
SCHEMBL6353583 0.98 MAOA (1.00) MAOAMAOBALDH1A1KDM4EHPGD
Hydrochloric Acid SCHEMBL11215152 0.95 MAOA (0.95) MAOAMAOBALDH1A1KDM4EHPGD
SCHEMBL12540036 0.95 MAOA (0.95) MAOAMAOBALDH1A1KDM4EHPGD
Bromide SCHEMBL7149637 0.95 MAOA (0.95) MAOAMAOBALDH1A1KDM4EHPGD
Benzene SCHEMBL18492989 0.95 MAOA (0.95) MAOAMAOBALDH1A1KDM4EHPGD
Water SCHEMBL11007472 0.95 MAOA (0.95) MAOAMAOBALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8192577-A None JP disclosed
JP-10016410-A None JP disclosed
JP-6228445-A None JP disclosed
JP-H1016410-A HEAT DECOLORING SUBSTANCE AND HEAT RECORDING MATERIAL AND HEAT DEVELOPMENT PHOTOSENSITIVE MATERIAL USING THE SUBSTANCE FUJI PHOTO FILM CO LTD 1998-01-20 JP disclosed
JP-H08192577-A COATING BLEND FOR HEAT-SENSITIVE PAPER CIBA GEIGY AG 1996-07-30 JP disclosed
US-5389489-A Support having coating layer with microcapsules containing leuco dye and photooxidizing agent, reducing agent FUJI PHOTO FILM CO., LTD. (JP) 1995-02-14 US disclosed
JP-H06228445-A LEUCO DYE FUJI PHOTO FILM CO LTD 1994-08-16 JP disclosed