Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | MGMT | P16455 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5091266 | 0.90 | PDPK1 (0.40) | PDPK1GDAKDRAURKBCDK2 | |
| SCHEMBL8594393 | 0.83 | CYP2C19 (0.30) | — | |
| SCHEMBL31239223 | 0.79 | PDPK1 (0.53) | PDPK1GDAKDRAURKBCDK2 | |
| SCHEMBL8592144 | 0.79 | PDPK1 (0.53) | PDPK1GDAKDRAURKBCDK2 | |
| SCHEMBL7758704 | 0.75 | PDE4A (0.39) | CDK2ADORA3HDAC1HDAC2MGMT | |
| SCHEMBL5091257 | 0.74 | CYP2C19 (0.30) | — | |
| SCHEMBL17165348 | 0.74 | GDA (0.53) | PDPK1GDAKDRAURKBCDK2 | |
| SCHEMBL10361596 | 0.72 | PDPK1 (0.45) | PDPK1GDAKDRAURKBCDK2 | |
| SCHEMBL31239073 | 0.72 | KDR (0.42) | KDRAURKBCDK2 | |
| SCHEMBL3134186 | 0.70 | HDAC1 (0.43) | PDPK1GDAKDRAURKBPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815259-A1 | MODULATION OF THE BINDING PROPERTIES OF NUCLEIC ACID BINDING PARTNERS | Roche Diagnostics GmbH (DE) | 1998-01-07 | — | — | EP | disclosed |
| EP-0813610-A1 | SEQUENCE-SPECIFIC DETECTION OF NUCLEIC ACIDS | Roche Diagnostics GmbH (DE) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996027680-A1 | SEQUENCE-SPECIFIC DETECTION OF NUCLEIC ACIDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-09-12 | — | — | WO | disclosed |
| WO-1996027679-A1 | MODULATION OF THE BINDING PROPERTIES OF NUCLEIC ACID BINDING PARTNERS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-09-12 | — | — | WO | disclosed |