SCHEMBL8593142

SCHEMBL8593142

Cc1cc(NCCNS(C)(=O)=O)ccc1NCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CRHBP P24387 1/20 0.49
CYP2C19 P33261 1/20 0.49
CRHR2 Q13324 1/20 0.49
POLB P06746 3/20 0.44
HTR6 P50406 1/20 0.42
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8629296 0.82 HTT (0.59) MAPTMEN1KMT2ACYP1A2CYP3A4
Sulfuric Acid SCHEMBL9564309 0.79 GAA (0.40) MAPTMEN1KMT2ACYP3A4CYP2C9
SCHEMBL9453024 0.79 RPS6KA2 (0.45) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL8593139 0.78 MAPT (0.47) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL8029824 0.74 GAA (0.39) MAPTPOLBHTTSMN1; SMN2ALDH1A1
SCHEMBL632638 0.74 POLB (0.55) MAPTMEN1KMT2APOLBHTT
SCHEMBL4822315 0.74 ALDH1A1 (0.41) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL9447751 0.73 MAPT (0.68) MAPTMEN1KMT2APOLBHTT
SCHEMBL11175667 0.71 MAPT (0.61) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL6422921 0.71 KMT2A (0.63) MAPTMEN1KMT2APOLBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0463639-B1 Color photographs and process for making the same FUJI PHOTO FILM CO LTD (JP) 1998-01-14 EP disclosed
EP-0255722-B1 COLOR PHOTOGRAPHS AND PROCESS FOR MAKING THE SAME FUJI PHOTO FILM CO., LTD. (JP) 1992-07-15 EP disclosed
US-5108876-A Storage stability improving compound FUJI PHOTO FILM CO., LTD. (JP) 1992-04-28 US disclosed
EP-0463639-A1 Color photographs and process for making the same FUJI PHOTO FILM CO., LTD. (JP) 1992-01-02 EP disclosed
US-4939072-A DEVELOPING IN PRESENCE OF STORAGE STABILITY IMPROVING COMPOUND WHICH FORMS COLORLESS SUBSTANCE BY REACTING WITH RESIDUAL DEVELOPER FUJI PHOTO FILM CO., LTD. (JP) 1990-07-03 US disclosed
EP-0255722-A2 Color photographs and process for making the same FUJI PHOTO FILM CO., LTD. (JP) 1988-02-10 EP disclosed