Sulfuric Acid

Sulfuric Acid

SCHEMBL9564309

CCNc1ccc(NCCNS(C)(=O)=O)cc1C.O=S(=O)(O)O

nearest known ligand 0.40

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
MAPT P10636 7/20 0.40
POLB P06746 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 1/20 0.39
KDM4D Q6B0I6 1/20 0.38
PKM P14618 1/20 0.37
ATM Q13315 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
RECQL P46063 1/20 0.36
NPC1 O15118 1/20 0.35
HTT P42858 1/20 0.33
CYP2C9 P11712 1/20 0.33
TDO2 P48775 1/20 0.33
GRIN1 Q05586 1/20 0.33
KCNH2 Q12809 1/20 0.33
GRIN2B Q13224 1/20 0.33
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL9300936 0.85 RECQL (0.43) GAAMAPTPOLBSMN1; SMN2ALDH1A1
Sulfuric Acid SCHEMBL28617571 0.85 ALDH1A1 (0.49) GAAMAPTPOLBALDH1A1PKM
SCHEMBL8029824 0.82 GAA (0.39) GAAMAPTPOLBSMN1; SMN2ALDH1A1
Sulfuric Acid SCHEMBL3453574 0.81 ALDH1A1 (0.42) GAAMAPTPOLBSMN1; SMN2ALDH1A1
Sulfuric Acid SCHEMBL11318250 0.80 ALDH1A1 (0.41) GAAMAPTPOLBSMN1; SMN2ALDH1A1
Sulfuric Acid SCHEMBL7031463 0.80 ALDH1A1 (0.41) GAAMAPTPOLBSMN1; SMN2ALDH1A1
SCHEMBL8593142 0.79 MAPT (0.49) GAAMAPTPOLBSMN1; SMN2ALDH1A1
Sulfuric Acid SCHEMBL9327543 0.78 NQO2 (0.40) GAAMAPTPOLBSMN1; SMN2ALDH1A1
Sulfuric Acid SCHEMBL10699624 0.77 ALDH1A1 (0.38) GAAMAPTPOLBSMN1; SMN2ALDH1A1
SCHEMBL7521178 0.76 MAPT (0.40) MAPTPOLBSMN1; SMN2ALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0569126-A1 Process of forming silver halide color photographic images KONICA CORPORATION (JP) 1993-11-10 EP disclosed