Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16317402 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTRAB9AL3MBTL1KMT2A | |
| SCHEMBL13714731 | 0.91 | BRD4 (0.44) | SMN1; SMN2MAPTRAB9AL3MBTL1KMT2A | |
| SCHEMBL19982707 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTRAB9AL3MBTL1KMT2A | |
| SCHEMBL15835231 | 0.89 | L3MBTL1 (0.56) | SMN1; SMN2MAPTRAB9AL3MBTL1KMT2A | |
| SCHEMBL1003870 | 0.86 | GAA (0.54) | SMN1; SMN2MAPTRAB9AL3MBTL1KMT2A | |
| SCHEMBL13435320 | 0.86 | MEN1 (0.47) | SMN1; SMN2MAPTRAB9AL3MBTL1KMT2A | |
| SCHEMBL9713054 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2L3MBTL1KMT2AGAAHSD17B10 | |
| SCHEMBL13752995 | 0.84 | RAB9A (0.59) | MAPTRAB9AKMT2AGAAMEN1 | |
| SCHEMBL328703 | 0.84 | KDM4E (0.61) | SMN1; SMN2MAPTL3MBTL1GAAHSD17B10 | |
| SCHEMBL13753066 | 0.84 | CES2 (0.48) | SMN1; SMN2MAPTRAB9AL3MBTL1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140127155-A1 | Smac mimetic dimers and trimers useful as anti-cancer agents | JOYANT PHARMACEUTICALS, INC (US) | 2014-05-08 | — | — | US | disclosed |
| US-8642554-B2 | Smac mimetic dimers and trimers useful as anti-cancer agents | JOYANT PHARMACEUTICALS, INC. (US) | 2014-02-04 | — | — | US | disclosed |
| US-8492468-B2 | Polypropylene resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-23 | — | — | US | disclosed |
| US-20110301268-A1 | POLYPROPYLENE RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-08 | — | — | US | disclosed |
| US-20090104151-A1 | SMAC MIMETIC DIMERS AND TRIMERS USEFUL AS ANTI-CANCER AGENTS | JOYANT PHARMACEUTICALS, INC (US) | 2009-04-23 | — | — | US | disclosed |
| US-7390351-B2 | Electrets and compounds useful in electrets | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-06-24 | — | — | US | disclosed |
| US-20070180997-A1 | ELECTRETS AND COMPOUNDS USEFUL IN ELECTRETS | 3M INNOVATIVE PROPERTIES COMPANY | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104151-A1 | SMAC MIMETIC DIMERS AND TRIMERS USEFUL AS ANTI-CANCER AGENTS | BID, BAD, BIRC3 | SMN1; SMN2 101/4885MAPT 3858/4885RAB9A 3494/4885 |
| US-20140127155-A1 | Smac mimetic dimers and trimers useful as anti-cancer agents | BID, BAD, BIRC3 | SMN1; SMN2 101/4885MAPT 3858/4885RAB9A 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.