Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 4/20 | 0.50 |
| ▸ | NT5E | P21589 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 6/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963100 | 0.91 | STING1 (0.47) | NT5ELMNASTING1ADORA3ADORA2A | |
| SCHEMBL6936922 | 0.90 | ADORA3 (0.51) | NT5ELMNASTING1ADORA3DNMT1 | |
| SCHEMBL22216550 | 0.90 | ADORA3 (0.54) | NT5ELMNAADORA3ADORA2AADORA2B | |
| SCHEMBL19961896 | 0.90 | ADORA3 (0.54) | NT5ELMNAADORA3ADORA2AADORA2B | |
| SCHEMBL4757808 | 0.90 | ADORA3 (0.54) | NT5ELMNAADORA3ADORA2AADORA2B | |
| SCHEMBL23813544 | 0.86 | STING1 (0.56) | AHCYLMNASTING1ADORA3ADORA2B | |
| SCHEMBL6895355 | 0.86 | STING1 (0.56) | AHCYLMNASTING1ADORA3ADORA2B | |
| SCHEMBL16271105 | 0.86 | STING1 (0.56) | AHCYLMNASTING1ADORA3ADORA2B | |
| SCHEMBL22983991 | 0.86 | STING1 (0.56) | AHCYLMNASTING1ADORA3ADORA2B | |
| SCHEMBL14946346 | 0.86 | STING1 (0.56) | AHCYLMNASTING1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670845-B1 | PROCESS FOR THE PREPARATION OF FLUDARABINE PHOSPHATE FROM GUANOSINE | SCHERING AG (DE) | 1998-01-14 | — | — | EP | disclosed |
| US-5668270-A | Process for the preparation of fludarabine or fludarabine phosphate from guanosine | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-09-16 | — | — | US | disclosed |
| US-5602246-A | Process for the preparation of fludarabine or fludarabine phosphate from guanosine | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |