⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533595 | 0.80 | — | — | |
| SCHEMBL8579001 | 0.78 | CA2 (0.33) | — | |
| SCHEMBL1070151 | 0.78 | — | — | |
| SCHEMBL2515992 | 0.78 | — | — | |
| SCHEMBL2471794 | 0.75 | — | — | |
| SCHEMBL8719762 | 0.71 | TP53 (0.31) | — | |
| SCHEMBL14813018 | 0.71 | TP53 (0.31) | — | |
| SCHEMBL2237802 | 0.71 | — | — | |
| SCHEMBL29813597 | 0.67 | — | — | |
| SCHEMBL898767 | 0.67 | CA2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102107146-B | Catalyst for synthesizing hexene-1 by ethylene trimerization and application thereof | PETROCHINA CO LTD | 2013-10-16 | — | — | CN | claimed |
| CN-102107146-B | Catalyst for synthesizing hexene-1 by ethylene trimerization and application thereof | PETROCHINA CO LTD | 2013-10-16 | — | — | CN | disclosed |
| CN-103044181-A | Method for preparing octene-1 by ethylene tetramerization reaction | PETROCHINA CO LTD | 2013-04-17 | — | — | CN | disclosed |
| CN-102107146-A | Catalyst for synthesizing hexene-1 by ethylene trimerization and application thereof | PETROCHINA CO LTD | 2011-06-29 | — | — | CN | disclosed |
| CN-101663276-A | 2-aminopyridine derivatives useful as kinase inhibitors | VERTEX PHARMA | 2010-03-03 | — | — | CN | disclosed |
| CN-100386149-C | Ethylene trimerization catalyst and application thereof | PETROCHINA CO LTD (CN) | 2008-05-07 | — | — | CN | disclosed |
| CN-1872416-A | Ethylene trimerization catalyst and application thereof | PETROCHINA CO LTD (CN) | 2006-12-06 | — | — | CN | disclosed |
| CN-1651142-A | Catalyst component used for ethylene oligomerization, preparing process and application thereof | DAQING PETROCHEMICAL BRANCH CO (CN) | 2005-08-10 | — | — | CN | disclosed |
| WO-1998007734-A9 | OLIGONUCLEOTIDE PRODRUGS | — | 1998-04-30 | — | — | WO | disclosed |
| WO-1998007734-A1 | OLIGONUCLEOTIDE PRODRUGS | HYBRIDON, INC. (US) | 1998-02-26 | — | — | WO | disclosed |
| EP-0370317-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-CHLOROPYRIDINES | BAYER AG (DE) | 1993-06-02 | — | — | EP | disclosed |