Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388570 | 0.80 | CCKBR (0.49) | CCKBRBDKRB1 | |
| SCHEMBL8552793 | 0.72 | CCKBR (0.48) | CCKBRBDKRB1 | |
| SCHEMBL9007294 | 0.71 | CCKBR (0.46) | CCKBR | |
| SCHEMBL1388598 | 0.67 | CCKBR (0.59) | CCKBR | |
| SCHEMBL9008724 | 0.67 | CCKBR (0.65) | CCKBRBDKRB1 | |
| SCHEMBL8646939 | 0.67 | CCKAR (0.55) | CCKBR | |
| SCHEMBL1388679 | 0.67 | CCKBR (0.53) | CCKBR | |
| Hydrochloric Acid SCHEMBL9007292 | 0.67 | CCKBR (0.58) | CCKBR | |
| SCHEMBL8555082 | 0.67 | SENP1 (0.44) | CCKBRBDKRB1 | |
| SCHEMBL8552604 | 0.67 | CCKBR (0.48) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |