Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 4/20 | 0.40 |
| ▸ | BRD2 | P25440 | 4/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.40 |
| ▸ | CCKBR | P32239 | 8/20 | 0.39 |
| ▸ | OXTR | P30559 | 2/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | CCKAR | P32238 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388570 | 0.86 | CCKBR (0.49) | CCKBRBDKRB1 | |
| SCHEMBL9007233 | 0.86 | SENP1 (0.49) | SENP1BRD4BRD2BRD3CCKBR | |
| SCHEMBL8555947 | 0.83 | HRH3 (0.38) | OXTR | |
| SCHEMBL8558106 | 0.82 | SENP1 (0.49) | SENP1BRD4BRD2BRD3CCKBR | |
| SCHEMBL8622534 | 0.80 | SENP1 (0.47) | SENP1BRD4BRD2BRD3CCKBR | |
| SCHEMBL8555087 | 0.79 | BRD4 (0.41) | SENP1BRD4BRD2BRD3CCKBR | |
| SCHEMBL8555248 | 0.77 | OXTR (0.41) | CCKBROXTRBDKRB1CCKAR | |
| SCHEMBL8554771 | 0.76 | CCKBR (0.49) | CCKBRCCKAR | |
| SCHEMBL8555289 | 0.75 | CCKBR (0.45) | CCKBROXTRCCKAR | |
| SCHEMBL8552793 | 0.74 | CCKBR (0.48) | CCKBRBDKRB1CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |