Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.60 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6496307 | 0.99 | POLB (0.69) | POLBALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL8667688 | 0.96 | ALDH1A1 (0.70) | POLBALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL8665529 | 0.94 | ALDH1A1 (0.68) | POLBALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL8664913 | 0.91 | POLB (0.75) | POLBALDH1A1CYP3A4CYP2C19CYP1A2 | |
| Iodoacetamide SCHEMBL8666719 | 0.90 | ALDH1A1 (0.63) | POLBALDH1A1CYP3A4CYP2C19CYP1A2 | |
| Hydrochloric Acid SCHEMBL8668067 | 0.90 | POLB (0.73) | POLBALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL21765989 | 0.89 | POLB (0.77) | POLBALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL9406540 | 0.87 | POLB (0.83) | POLBALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL9844925 | 0.85 | POLB (0.81) | POLBALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL6243622 | 0.85 | ALDH1A1 (0.71) | POLBALDH1A1CYP3A4CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843634-A | Genetically engineered enzymes and their conjugates for diagnostic assays | ABBOTT LABORATORIES (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0648328-B1 | IMPROVEMENT IN OPTICAL ASSAYS | BIACORE AKTIEBOLAG (SE) | 1998-01-21 | — | — | EP | disclosed |
| EP-0688364-A4 | GENETICALLY ENGINEERED ENZYMES AND THEIR CONJUGATES FOR DIAGNOSTIC ASSAYS | ABBOTT LAB (US) | 1997-10-15 | — | — | EP | disclosed |
| US-5643734-A | KITS FOR QUALITATIVE AND QUANTITATIVE ANALYSIS | MICROGENICS CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| US-5641640-A | MEASURING CHANGE IN REFRACTIVE INDEX, VARYING WAVELENGTH | BIACORE AB (SE) | 1997-06-24 | — | — | US | disclosed |
| US-5604091-A | ENZYME DONOR POLYPEPTIDE HAVING SPECIFIED AMINO ACID SEQUENCE; QUALITATIVE AND QUANTITATIVE ANALYSIS | MICROGENICS CORPORATION (US) | 1997-02-18 | — | — | US | disclosed |
| EP-0599956-B1 | ASSAY METHOD | PHARMACIA BIOSENSOR AB (SE) | 1997-02-05 | — | — | EP | disclosed |
| US-5573956-A | Assay method based upon refractive index changes at a solid optical surface | PHARMACIA BIOSENSOR AB (SE) | 1996-11-12 | — | — | US | disclosed |
| EP-0589867-B1 | SENSING SURFACES CAPABLE OF SELECTIVE BIOMOLECULAR INTERACTIONS, TO BE USED IN BIOSENSOR SYSTEMS | PHARMACIA BIOSENSOR AB (SE) | 1996-04-10 | — | — | EP | disclosed |
| US-5492840-A | Surface plasmon resonance sensor unit and its use in biosensor systems | PHARMACIA BIOSENSOR AB (SE) | 1996-02-20 | — | — | US | disclosed |
| EP-0199801-A1 | METHODS FOR PROTEIN BINDING ENZYME COMPLEMENTATION ASSAYS. | MICROGENICS CORP (US) | 1986-11-05 | — | — | EP | disclosed |
| WO-1986002666-A1 | METHODS FOR PROTEIN BINDING ENZYME COMPLEMENTATION ASSAYS | MICROGENICS CORPORATION (US) | 1986-05-09 | — | — | WO | disclosed |
| EP-0069281-B1 | MULTILAYER ANALYTICAL ELEMENT; METHOD FOR ITS PREPARATION AND ITS USE IN ANALYTICAL METHODS | MILES INC. (US) | 1985-09-25 | — | — | EP | disclosed |
| US-4447529-A | IMMUNOASSAY; AMINOGLYCOSIDE ANTIBIOTICS; STRIPS | MILES LABORATORIES, INC. (US) | 1984-05-08 | — | — | US | disclosed |
| US-4404366-A | ENZYME CLEAVABLE GLYCOSIDIC LINKAGE | MILES LABORATORIES, INC. (US) | 1983-09-13 | — | — | US | disclosed |
| US-4390343-A | Multilayer analytical element having an impermeable radiation diffusing and blocking layer | MILES LABORATORIES, INC. (US) | 1983-06-28 | — | — | US | disclosed |
| EP-0069281-A1 | Multilayer analytical element; method for its preparation and its use in analytical methods | MILES INC. (US) | 1983-01-12 | — | — | EP | disclosed |
| US-4363874-A | RADIOIMMUNOASSAY DIAGNOSIS | MILES LABORATORIES, INC. (US) | 1982-12-14 | — | — | US | disclosed |
| US-4331590-A | β-Galactosyl-umbelliferone-labeled protein and polypeptide conjugates | MILES LABORATORIES, INC. (US) | 1982-05-25 | — | — | US | disclosed |
| US-4279992-A | Specific binding assay employing an enzyme-cleavable substrate as label | MILES LABORATORIES, INC. (US) | 1981-07-21 | — | — | US | disclosed |