Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.75 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394217 | 0.94 | POLB (0.78) | POLBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL16084377 | 0.94 | POLB (0.78) | POLBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4222552 | 0.94 | POLB (0.78) | POLBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL19969306 | 0.93 | ALDH1A1 (0.72) | POLBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL8665529 | 0.93 | ALDH1A1 (0.68) | POLBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL9844925 | 0.92 | POLB (0.81) | POLBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL8667688 | 0.91 | ALDH1A1 (0.70) | POLBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL10652432 | 0.91 | ALDH1A1 (0.74) | POLBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL10654293 | 0.91 | ALDH1A1 (0.70) | POLBALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL9406540 | 0.91 | POLB (0.83) | POLBALDH1A1CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634434-B2 | Bifunctional alpha-synuclein binding agents and uses thereof | UNIVERSITY OF SASKATCHEWAN (CA) | 2023-04-25 | — | — | US | disclosed |
| US-20200062782-A1 | BIFUNCTIONAL ALPHA-SYNUCLEIN BINDING AGENTS AND USES THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062782-A1 | BIFUNCTIONAL ALPHA-SYNUCLEIN BINDING AGENTS AND USES THEREOF | SNCA, PARK7, SYNJ2 | POLB 931/4885ALDH1A1 2050/4885CYP2C19 4783/4885 |
| US-11634434-B2 | Bifunctional alpha-synuclein binding agents and uses thereof | SNCA, PARK7, SYNJ2 | POLB 931/4885ALDH1A1 2050/4885CYP2C19 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.