Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771388 | 0.90 | PARP1 (0.46) | PARP1MAPTALDH1A1HPGDPOLB | |
| SCHEMBL1886429 | 0.82 | ACHE (0.43) | PARP1 | |
| SCHEMBL8670123 | 0.80 | HIF1A (0.49) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL9257694 | 0.80 | — | — | |
| SCHEMBL1895574 | 0.79 | PPARG (0.52) | — | |
| SCHEMBL27771406 | 0.79 | ALDH1A1 (0.44) | PARP1MAPTALDH1A1HPGDPOLB | |
| SCHEMBL27771413 | 0.78 | BRS3 (0.39) | PARP1MAPTALDH1A1HPGDTUBB4A | |
| SCHEMBL28236562 | 0.78 | ALDH1A1 (0.50) | PARP1MAPTALDH1A1HPGDPOLB | |
| SCHEMBL9129778 | 0.76 | — | — | |
| SCHEMBL9196627 | 0.75 | AGTR1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593332-B1 | Phenylborinic acid derivatives, their preparation and their use as intermediates in syntheses | SYNTHELABO (FR) | 1998-01-14 | — | — | EP | disclosed |
| EP-0655452-A1 | Triarylborane derivatives, their preparation and their use as intermediates | SYNTHELABO (FR) | 1995-05-31 | — | — | EP | disclosed |
| US-5405960-A | Triarylborane derivatives, their preparation and their use as synthesis intermediates | SYNTHELABO (FR) | 1995-04-11 | — | — | US | disclosed |
| US-5382672-A | Preparation of derivatives of benzeneborinic acid | SYNTHELABO (FR) | 1995-01-17 | — | — | US | disclosed |
| US-5374735-A | Triarylborane derivatives, their preparation and their use as synthesis intermediates | SYNTHELABO (FR) | 1994-12-20 | — | — | US | disclosed |
| US-5312920-A | Process for preparing 4-pyrimidinones | SYNTHELABO (FR) | 1994-05-17 | — | — | US | disclosed |
| EP-0593332-A1 | Phenylboronic acid derivatives, their preparation and their use as intermediates in syntheses | SYNTHELABO (FR) | 1994-04-20 | — | — | EP | disclosed |
| US-5278312-A | Derivatives of benzeneborinic acid, preparation thereof and use thereof as synthetic intermediates | SYNTHELABO (FR) | 1994-01-11 | — | — | US | disclosed |
| EP-0561664-A1 | Process for the preparation of 4-pyrimidines | SYNTHELABO (FR) | 1993-09-22 | — | — | EP | disclosed |