SCHEMBL8595668

SCHEMBL8595668

O=C(O)c1ccc(C(=O)O)c2c1-c1ccc3ccccc3c1-2

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.76
LDHA P00338 1/20 0.58
NR4A1 P22736 1/20 0.53
NR4A2 P43354 1/20 0.53
NR4A3 Q92570 1/20 0.53
SOS1 Q07889 3/20 0.53
CDC25B P30305 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46
HIF1A Q16665 1/20 0.46
ALDH1A1 P00352 3/20 0.45
HPGD P15428 3/20 0.45
KDM4E B2RXH2 2/20 0.45
DNMT1 P26358 1/20 0.44
LMNA P02545 1/20 0.44
CSNK2A2 P19784 1/20 0.44
CSNK2B P67870 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29721418 0.87 WDR5 (1.00) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL895573 0.87 WDR5 (1.00) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL29795098 0.85 WDR5 (0.74) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL29458346 0.84 WDR5 (0.79) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL9124028 0.84 WDR5 (0.79) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL2240626 0.81 WDR5 (0.81) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL23815788 0.81 WDR5 (0.79) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL6243613 0.80 WDR5 (0.67) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL29265485 0.79 WDR5 (0.71) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL5070846 0.79 WDR5 (0.71) WDR5LDHANR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0533931-B1 FABRIC MADE FROM BLENDED YARN COMPRISING AROMATIC POLYAMIDE FIBER AND POLYESTER FIBER TEIJIN LTD (JP) 1998-01-21 EP claimed
US-5356700-A Flame-resistant clothing TEIJIN LIMITED (JP) 1994-10-18 US claimed
EP-0533931-A1 FABRIC MADE FROM BLENDED YARN COMPRISING AROMATIC POLYAMIDE FIBER AND POLYESTER FIBER TEIJIN LIMITED (JP) 1993-03-31 EP claimed
EP-0533931-B1 FABRIC MADE FROM BLENDED YARN COMPRISING AROMATIC POLYAMIDE FIBER AND POLYESTER FIBER TEIJIN LTD (JP) 1998-01-21 EP disclosed
US-5356700-A Flame-resistant clothing TEIJIN LIMITED (JP) 1994-10-18 US disclosed
EP-0533931-A1 FABRIC MADE FROM BLENDED YARN COMPRISING AROMATIC POLYAMIDE FIBER AND POLYESTER FIBER TEIJIN LIMITED (JP) 1993-03-31 EP disclosed