Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | USP19 | O94966 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935422 | 0.87 | DPP4 (0.46) | DPP4DPP7RIPK1TAAR1SLC18A3 | |
| SCHEMBL20528485 | 0.87 | DPP4 (0.46) | DPP4DPP7RIPK1TAAR1SLC18A3 | |
| SCHEMBL21801033 | 0.87 | DPP4 (0.46) | DPP4DPP7RIPK1TAAR1SLC18A3 | |
| SCHEMBL7749807 | 0.87 | RIPK1 (0.46) | DPP4DPP7RIPK1TAAR1SLC18A3 | |
| Hydrochloric Acid SCHEMBL9258072 | 0.86 | DPP4 (0.46) | DPP4DPP7RIPK1TAAR1SLC18A3 | |
| SCHEMBL8498489 | 0.85 | DPP4 (0.41) | DPP4DPP7RIPK1HTR2AHTR2C | |
| SCHEMBL2386164 | 0.84 | DPP4 (0.47) | DPP4DPP7RIPK1TAAR1SLC18A3 | |
| SCHEMBL1580100 | 0.84 | POLB (0.54) | DPP4DPP7RIPK1TAAR1SLC18A3 | |
| SCHEMBL8595774 | 0.83 | SIGMAR1 (0.53) | DPP4DPP7RIPK1HTR2CSIGMAR1 | |
| Hydrochloric Acid SCHEMBL28773228 | 0.83 | DPP4 (0.46) | DPP4DPP7RIPK1TAAR1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552417-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0528312-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-07-16 | — | — | EP | disclosed |