SCHEMBL8596032

SCHEMBL8596032

C=CCOc1cc(-c2ccccn2)ccc1CCCCCC(C)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SQOR Q9Y6N5 1/20 0.38
DCTPP1 Q9H773 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP19A1 P11511 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
ERN1 O75460 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MGLL Q99685 1/20 0.33
OPRD1 P41143 2/20 0.32
NR1D1 P20393 1/20 0.32
S1PR1 P21453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8600729 0.89 KDM4E (0.32) CYP1A2CYP2D6KDM4EMEN1NPC1
SCHEMBL8597870 0.87 CYP2D6 (0.36) CYP2D6CYP19A1CYP2C9CYP2C19MGLL
SCHEMBL8596620 0.86 DCTPP1 (0.41) SQORDCTPP1CYP1A2CYP2D6CYP19A1
SCHEMBL8600854 0.84 CYP1A2 (0.34) SQORCYP1A2CYP2D6CYP19A1CYP2C9
SCHEMBL8596830 0.82 HDAC1 (0.32)
SCHEMBL8603690 0.82 SQOR (0.38) SQORDCTPP1
SCHEMBL8597098 0.80 SQOR (0.33) SQORCYP1A2CYP2D6CYP19A1CYP2C9
SCHEMBL8601977 0.80 SQOR (0.39) SQORDCTPP1CYP1A2CYP2D6CYP19A1
SCHEMBL8601985 0.79 SQOR (0.38) SQORDCTPP1CYP1A2CYP2D6CYP19A1
SCHEMBL8601305 0.76 PDE4A (0.34) SQOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5779934-A FLUORINATING AN ALCOHOL DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed