Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.34 |
| ▸ | PTAFR | P25105 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603690 | 0.90 | SQOR (0.38) | PDE4APDE4BPDE4CPDE4DLTA4H | |
| SCHEMBL8599817 | 0.85 | PORCN (0.34) | PTAFRLTA4HPOLB | |
| SCHEMBL8602905 | 0.84 | PTAFR (0.37) | PTAFRPOLB | |
| SCHEMBL8600729 | 0.82 | KDM4E (0.32) | PTAFRLTA4H | |
| SCHEMBL8602158 | 0.82 | KDM4E (0.32) | SQOR | |
| SCHEMBL8602621 | 0.81 | SQOR (0.31) | SQOR | |
| SCHEMBL8604338 | 0.80 | CYP11B1 (0.42) | PTAFRLTA4HPOLB | |
| SCHEMBL7556418 | 0.79 | CYP2D6 (0.39) | POLB | |
| SCHEMBL8598085 | 0.79 | CYP2D6 (0.39) | POLB | |
| SCHEMBL8598821 | 0.79 | LTA4H (0.35) | LTA4HPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |