SCHEMBL8520132

SCHEMBL8520132

C=CCSc1nc2nc(C)cc(O)n2n1

nearest known ligand 0.75

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.67
ABCB1 P08183 1/20 0.58
ALDH1A1 P00352 3/20 0.52
KDM4E B2RXH2 1/20 0.50
CYP1A2 P05177 1/20 0.50
UBE2M P61081 1/20 0.49
DCUN1D1 Q96GG9 1/20 0.49
PTPN11 Q06124 1/20 0.48
HPGD P15428 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
RECQL P46063 1/20 0.45
ALOX15 P16050 1/20 0.44
POLB P06746 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
ATM Q13315 1/20 0.43
CKS1B P61024 1/20 0.42
SKP2 Q13309 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10623008 0.78 SMN1; SMN2 (0.57) KDM1AALDH1A1KDM4ECYP1A2HPGD
SCHEMBL13996431 0.78 ALDH1A1 (0.59) KDM1AALDH1A1KDM4ECYP1A2HPGD
SCHEMBL2315537 0.77 ALDH1A1 (0.57) KDM1AALDH1A1KDM4ECYP1A2HPGD
SCHEMBL5688394 0.76 ALDH1A1 (0.56) KDM1AALDH1A1KDM4ECYP1A2HPGD
SCHEMBL8596179 0.76 SMN1; SMN2 (0.47) KDM1AABCB1ALDH1A1KDM4EUBE2M
SCHEMBL4612108 0.74 ALDH1A1 (0.46) ALDH1A1KDM4ECYP1A2UBE2MDCUN1D1
SCHEMBL8406523 0.73 CYP1A2 (0.50) KDM1AABCB1ALDH1A1KDM4ECYP1A2
SCHEMBL8403913 0.72 CYP1A2 (0.49) KDM1AABCB1ALDH1A1KDM4ECYP1A2
SCHEMBL8406580 0.72 CYP1A2 (0.49) KDM1AABCB1ALDH1A1KDM4ECYP1A2
SCHEMBL8406579 0.72 CYP1A2 (0.49) KDM1AABCB1ALDH1A1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0574331-B1 Tone control of photographic images EASTMAN KODAK CO (US) 1999-07-28 EP disclosed
EP-0573373-B1 Tone control of photographic silver images EASTMAN KODAK CO (US) 1999-07-14 EP disclosed
EP-0575262-B1 Radiographic elements with improved covering power EASTMAN KODAK CO (US) 1999-07-07 EP disclosed
US-5314790-A Tetrazoles or triazoles EASTMAN KODAK COMPANY (US) 1994-05-24 US disclosed
US-5292627-A Azole to modify tone EASTMAN KODAK COMPANY (US) 1994-03-08 US disclosed
US-5292631-A Radiographic elements with improved covering power EASTMAN KODAK COMPANY (US) 1994-03-08 US disclosed
EP-0575262-A2 Radiographic elements with improved covering power EASTMAN KODAK COMPANY (US) 1993-12-22 EP disclosed
EP-0574331-A2 Tone control of photographic images EASTMAN KODAK COMPANY (US) 1993-12-15 EP disclosed
EP-0573373-A2 Tone control of photographic silver images EASTMAN KODAK COMPANY (US) 1993-12-08 EP disclosed