SCHEMBL9814583

SCHEMBL9814583

CSc1nc2nccc(O)n2n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 14/20 0.56
ALDH1A1 P00352 10/20 0.56
HPGD P15428 8/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
MAPT P10636 3/20 0.56
NPSR1 Q6W5P4 3/20 0.56
POLB P06746 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
CTDSP1 Q9GZU7 1/20 0.56
MEN1 O00255 1/20 0.54
LMNA P02545 1/20 0.54
KMT2A Q03164 1/20 0.54
HTT P42858 1/20 0.50
RAB9A P51151 2/20 0.41
RXFP1 Q9HBX9 1/20 0.41
HSD17B10 Q99714 2/20 0.40
DYRK3 O43781 1/20 0.35
DYRK1A Q13627 1/20 0.35
DYRK2 Q92630 1/20 0.35
ADORA3 P0DMS8 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1022307 0.78 POLB (0.42) KDM4EALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL2315537 0.72 ALDH1A1 (0.57) KDM4EALDH1A1HPGDSMN1; SMN2POLB
SCHEMBL5688394 0.71 ALDH1A1 (0.56) KDM4EALDH1A1HPGDSMN1; SMN2POLB
SCHEMBL13140142 0.70 KDM4E (0.41) KDM4EALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL9678977 0.68 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2POLBTDP1MEN1
SCHEMBL11035817 0.66 KDM4E (0.49) KDM4EALDH1A1SMN1; SMN2MAPTPOLB
SCHEMBL7066910 0.64 NPC1 (0.56) KDM4EALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL1131654 0.63
SCHEMBL31553149 0.63 LMNA (0.47) KDM4EALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL6230658 0.63 KDM4E (0.40) KDM4EALDH1A1HPGDSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0213964-B1 SILVER HALIDE PHOTOGRAPHIC EMULSIONS WITH NOVEL GRAIN FACES (3) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-07-31 EP claimed
US-4680256-A Emulsions and photographic elements containing silver halide grains having trisoctahedra crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US claimed
EP-0213964-A2 Silver halide photographic emulsions with novel grain faces (3) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-03-11 EP claimed
WO-2025233865-A1 ENPP1 INHIBITORS RE VENTURES I, LLC (US) 2025-11-13 WO disclosed
US-9963451-B2 Fused ring pyrimidine compound and pest control agent containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2018-05-08 US disclosed
US-20150368249-A1 FUSED RING PYRIMIDINE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2015-12-24 US disclosed
EP-0213964-B1 SILVER HALIDE PHOTOGRAPHIC EMULSIONS WITH NOVEL GRAIN FACES (3) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-07-31 EP disclosed
US-4724200-A CRYSTAL STRUCTURE EASTMAN KODAK COMPANY (US) 1988-02-09 US disclosed
US-4680255-A Emulsions and photographic elements containing silver halide grains having tetrahexahedral crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed
US-4680256-A Emulsions and photographic elements containing silver halide grains having trisoctahedra crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed
US-4680254-A Emulsions and photographic elements containing silver halide grains having hexoctamedral crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368249-A1 FUSED RING PYRIMIDINE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME CBR3, HRH2, HRH4 KDM4E 1972/4885ALDH1A1 3675/4885HPGD 2539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.