Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592782 | 0.84 | ALDH1A1 (0.43) | ALDH1A1IDO1TDO2MAPTNPSR1 | |
| SCHEMBL8596717 | 0.84 | ALDH1A1 (0.41) | ALDH1A1IDO1TDO2HDAC4HDAC7 | |
| SCHEMBL8593031 | 0.83 | NR3C1 (0.41) | ALDH1A1IDO1TDO2HDAC3HDAC4 | |
| SCHEMBL566014 | 0.79 | TYR (0.48) | ALDH1A1IDO1TDO2HDAC3HDAC4 | |
| SCHEMBL28376765 | 0.78 | MAOA (0.44) | ALDH1A1NR3C1KMT2AMAOAMAOB | |
| SCHEMBL8594392 | 0.75 | CYP3A4 (0.45) | ALDH1A1IDO1TDO2BRD4MAPT | |
| SCHEMBL8594390 | 0.75 | CYP3A4 (0.45) | ALDH1A1IDO1TDO2BRD4MAPT | |
| SCHEMBL5518530 | 0.73 | IGF1R (0.46) | IDO1TDO2HDAC3HDAC4HDAC1 | |
| SCHEMBL21773853 | 0.73 | CA12 (0.40) | ALDH1A1MAPTL3MBTL1KMT2AMAOA | |
| SCHEMBL18003486 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1037176-C | Benzenealkanoic acids for cardiovascular diseases | PFIZER RES & DEV (IE) | 1998-01-28 | — | — | CN | disclosed |
| EP-0662950-B1 | BENZENEALKANOIC ACIDS FOR CARDIOVASCULAR DISEASES | PFIZER LTD (GB) | 1998-01-14 | — | — | EP | disclosed |
| US-5618941-A | Benzenealkanoic acids for cardiovascular diseases | PFIZER INC. (US) | 1997-04-08 | — | — | US | disclosed |
| CN-1087080-A | The phenyl alkane acids class of treatment cardiovascular disorder | PFIZER RES & DEV (IE) | 1994-05-25 | — | — | CN | disclosed |