Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626672 | 0.81 | CA12 (0.33) | — | |
| SCHEMBL8602041 | 0.80 | KDM4E (0.38) | KDM4EHTTKMT2A | |
| SCHEMBL8598890 | 0.80 | TSHR (0.34) | KDM4EKMT2A | |
| SCHEMBL8567243 | 0.77 | CA2 (0.38) | ALDH1A1MAPT | |
| SCHEMBL8560405 | 0.76 | NT5E (0.43) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL8596090 | 0.76 | TXNRD1 (0.41) | ALDH1A1LMNAMAPTHTTBLM | |
| SCHEMBL8562052 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL8602563 | 0.75 | ALDH1A1 (0.42) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL8596876 | 0.75 | ALDH1A1 (0.39) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL8596319 | 0.75 | ALDH1A1 (0.32) | ALDH1A1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |