Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595024 | 1.00 | DRD4 (0.55) | DRD4GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL8595026 | 1.00 | DRD4 (0.55) | DRD4GRIN1GRIN2BGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL8595172 | 0.99 | DRD4 (0.54) | DRD4GRIN1GRIN2BGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL8598902 | 0.99 | DRD4 (0.54) | DRD4GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL8597349 | 0.85 | POLB (0.55) | CHRM4POLBL3MBTL1 | |
| SCHEMBL10734821 | 0.85 | GRIN2B (0.64) | GRIN1GRIN2BCHRM4POLB | |
| SCHEMBL8594557 | 0.84 | ALDH1A1 (0.57) | DRD4GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL10735790 | 0.81 | GRIN2B (0.59) | GRIN1GRIN2BCHRM4 | |
| SCHEMBL8594621 | 0.80 | ADRA1A (0.78) | DRD4GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL8597517 | 0.80 | ADRA1A (0.78) | DRD4GRIN1GRIN2BGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648744-A1 | Phenylalkanolamine derivatives as antagonists of the NMDA receptor | F. HOFFMANN-LA ROCHE AG (CH) | 1995-04-19 | — | — | EP | claimed |
| EP-0648744-B1 | Phenylalkanolamine derivatives as antagonists of the NMDA receptor | HOFFMANN LA ROCHE (CH) | 1998-01-21 | — | — | EP | disclosed |
| EP-0648744-A1 | Phenylalkanolamine derivatives as antagonists of the NMDA receptor | F. HOFFMANN-LA ROCHE AG (CH) | 1995-04-19 | — | — | EP | disclosed |