Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993582 | 0.93 | KMT2A (0.50) | MEN1KMT2ACYP3A4HPGDMAPT | |
| SCHEMBL11276739 | 0.86 | NR4A2 (0.58) | MEN1KMT2ACYP3A4HPGDMAPT | |
| SCHEMBL7701997 | 0.79 | POLB (0.57) | MEN1KMT2ACYP3A4HPGDMAPT | |
| SCHEMBL6994495 | 0.78 | KMT2A (0.44) | MEN1KMT2ACYP3A4HPGDMAPT | |
| SCHEMBL5931323 | 0.77 | KMT2A (0.61) | MEN1KMT2ACYP3A4HPGDMAPT | |
| SCHEMBL1271165 | 0.76 | KMT2A (0.73) | MEN1KMT2ACYP3A4HPGDMAPT | |
| Phenylthioacetylglycine SCHEMBL11381408 | 0.76 | AKR1B1 (0.54) | MEN1KMT2AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL9129270 | 0.76 | KMT2A (0.59) | MEN1KMT2ACYP3A4HPGDMAPT | |
| SCHEMBL98540 | 0.75 | KMT2A (0.80) | MEN1KMT2ACYP3A4HPGDMAPT | |
| Dibenzoylmethane SCHEMBL1704711 | 0.75 | MEN1 (1.00) | MEN1KMT2ACYP3A4HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710228-B1 | HYDRAZINO-TYPE RADIONUCLIDE CHELATORS HAVING AN N 3?S CONFIGURATION | RESOLUTION PHARM INC (CA) | 1998-01-21 | — | — | EP | disclosed |
| US-5659041-A | MEDICAL DIAGNOSIS, THERAPY | RESOLUTION PHARMACEUTICALS, INC. (CA) | 1997-08-19 | — | — | US | disclosed |
| EP-0710228-A1 | HYDRAZINO-TYPE RADIONUCLIDE CHELATORS HAVING AN N 3?S CONFIGURATION | RESOLUTION PHARMACEUTICALS INC. (CA) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003280-A1 | HYDRAZINO-TYPE RADIONUCLIDE CHELATORS HAVING AN N3S CONFIGURATION | RESOLUTION PHARMACEUTICALS INC. (CA) | 1995-02-02 | — | — | WO | disclosed |