Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989814 | 0.86 | NR4A2 (0.42) | KMT2ASMN1; SMN2MAPTMEN1CYP3A4 | |
| SCHEMBL6991984 | 0.79 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2MAPTMEN1CYP3A4 | |
| SCHEMBL8596365 | 0.78 | MEN1 (0.57) | KMT2ASMN1; SMN2MAPTMEN1CYP3A4 | |
| SCHEMBL6993582 | 0.73 | KMT2A (0.50) | KMT2ASMN1; SMN2MAPTMEN1CYP3A4 | |
| SCHEMBL9352755 | 0.71 | KMT2A (0.44) | KMT2ASMN1; SMN2MAPTMEN1CYP3A4 | |
| SCHEMBL5931323 | 0.68 | KMT2A (0.61) | KMT2ASMN1; SMN2MAPTMEN1CYP3A4 | |
| SCHEMBL8725848 | 0.67 | GPR139 (0.56) | KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL11285319 | 0.67 | MAPT (0.52) | KMT2ASMN1; SMN2MAPTMEN1CYP3A4 | |
| SCHEMBL1271165 | 0.66 | KMT2A (0.73) | KMT2ASMN1; SMN2MAPTMEN1CYP3A4 | |
| SCHEMBL9129270 | 0.66 | KMT2A (0.59) | KMT2ASMN1; SMN2MAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606683-B1 | Means for diagnosis of angiogenic diseases | DIAGNOSTIKFORSCHUNG INST (DE) | 2003-01-02 | — | — | EP | claimed |
| US-6342201-B1 | COMPLEXES WHICH ENRICH ARTERIOSCLEROTIC PLAQUE AND ARE PREFERENTIALLY SUITED FOR NON-INVASIVE DIAGNOSIS OF ARTERIOSCLEROSIS | INSTITUT FOR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT (DE) | 2002-01-29 | — | — | US | disclosed |