Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596365 | 0.93 | MEN1 (0.57) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL11276739 | 0.80 | NR4A2 (0.58) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL10790420 | 0.79 | KMT2A (0.41) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL9724358 | 0.78 | PRSS1 (0.41) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL7293621 | 0.78 | KDM4E (0.59) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7515133 | 0.78 | KDM4E (0.59) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL9724366 | 0.77 | PARP1 (0.39) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL11064591 | 0.76 | ALDH1A1 (0.67) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL8865315 | 0.75 | ABAT (0.44) | KMT2ASMN1; SMN2ABATCYP2C19HIF1A | |
| SCHEMBL7701997 | 0.73 | POLB (0.57) | KMT2AMEN1CYP3A4HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606683-B1 | Means for diagnosis of angiogenic diseases | DIAGNOSTIKFORSCHUNG INST (DE) | 2003-01-02 | — | — | EP | claimed |
| EP-0606683-B1 | Means for diagnosis of angiogenic diseases | DIAGNOSTIKFORSCHUNG INST (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-6342201-B1 | COMPLEXES WHICH ENRICH ARTERIOSCLEROTIC PLAQUE AND ARE PREFERENTIALLY SUITED FOR NON-INVASIVE DIAGNOSIS OF ARTERIOSCLEROSIS | INSTITUT FOR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT (DE) | 2002-01-29 | — | — | US | disclosed |
| EP-0772633-A1 | COMPLEXES FOR USE IN THE DIAGNOSIS OF VASCULAR DISEASES | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002568-A1 | COMPLEXES FOR USE IN THE DIAGNOSIS OF VASCULAR DISEASES | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |
| EP-0606683-A2 | Means for diagnosis of angiogenic diseases | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5185433-A | Cross-linking protein compositions having two or more identical binding sites | CENTOCOR, INC. (US) | 1993-02-09 | — | — | US | disclosed |
| US-5162505-A | Proteins modified with positively charged carriers and compositions prepared therefrom | CENTOCOR (US) | 1992-11-10 | — | — | US | disclosed |
| US-5144043-A | Coupling protein or peptide to radionucleotide; labeling antibodies | CENTOCOR (US) | 1992-09-01 | — | — | US | disclosed |