Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ABAT | P80404 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436205 | 0.85 | POLB (0.69) | POLBALDH1A1SMN1; SMN2ALOX12GAA | |
| SCHEMBL9489778 | 0.81 | ALDH1A1 (0.52) | ABATALDH1A1SMN1; SMN2ALOX12KMT2A | |
| SCHEMBL8596365 | 0.79 | MEN1 (0.57) | ABATALDH1A1SMN1; SMN2ALOX12GAA | |
| Hippuric Acid SCHEMBL7486 | 0.78 | GAA (0.68) | POLBSMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL22030672 | 0.78 | GAA (0.68) | POLBSMN1; SMN2GAAKDM4EMAPT | |
| Hippuric Acid SCHEMBL428479 | 0.78 | GAA (0.68) | POLBSMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL7701085 | 0.78 | LMNA (0.52) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL28664923 | 0.77 | ALDH1A1 (0.78) | POLBABATALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL6085598 | 0.77 | PTPRC (0.49) | POLBALDH1A1KDM4ETDP1MGLL | |
| SCHEMBL4509905 | 0.77 | PPID (0.57) | POLBALDH1A1SMN1; SMN2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |