SCHEMBL859698

SCHEMBL859698

O=C(ON1C(=O)c2ccc(C(=O)c3ccc4c(c3)C(=O)N(OC(=O)c3ccccc3)C4=O)cc2C1=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.52
KMT2A Q03164 3/20 0.50
POLB P06746 2/20 0.50
MEN1 O00255 2/20 0.47
ENPP2 Q13822 2/20 0.47
ALDH1A1 P00352 5/20 0.46
TSHR P16473 1/20 0.46
HPGD P15428 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
TDP1 Q9NUW8 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
PTPRC P08575 1/20 0.42
ACHE P22303 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491136 0.85 ALDH1A1 (0.57) KMT2APOLBALDH1A1TSHRHPGD
SCHEMBL29082812 0.84 ALDH1A1 (0.56) KMT2APOLBALDH1A1TSHRHPGD
SCHEMBL860087 0.84 TDP1 (0.52) KMT2APOLBMEN1ALDH1A1CYP1A2
SCHEMBL16142447 0.84 ALDH1A1 (0.50) KMT2APOLBALDH1A1HPGDCYP1A2
SCHEMBL860092 0.80 ALDH1A1 (0.49) APEX1KMT2APOLBENPP2ALDH1A1
SCHEMBL859699 0.79 ALDH1A1 (0.43) APEX1KMT2APOLBMEN1ENPP2
SCHEMBL860121 0.79 ALDH1A1 (0.41) APEX1KMT2APOLBMEN1ENPP2
SCHEMBL22957153 0.79 ALDH1A1 (0.50) KMT2APOLBALDH1A1HPGDCYP1A2
SCHEMBL11756900 0.79 ALDH1A1 (0.49) KMT2APOLBALDH1A1HPGDCYP1A2
SCHEMBL860276 0.78 TUBB4A (0.50) ALDH1A1TSHRCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142983-B2 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-8142983-B2 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20090233229-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed
US-20090233229-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed
EP-2100731-A2 Lithographic printing plate precursor and method of lithographic printing Fujifilm Corporation (JP) 2009-09-16 EP disclosed