Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 2/20 | 0.40 |
| ▸ | ALPP | P05187 | 1/20 | 0.40 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597965 | 0.88 | CA12 (0.43) | MMP2CA12CA1CA2CA3 | |
| SCHEMBL8569083 | 0.87 | MMP2 (0.43) | MMP2MAPTSMN1; SMN2HTTSLC16A3 | |
| SCHEMBL8597093 | 0.86 | MMP2 (0.42) | MMP2MAPTSMN1; SMN2HTTSLC16A3 | |
| SCHEMBL8601890 | 0.86 | TNF (0.46) | MMP2SMN1; SMN2HTTSLC16A3RAB9A | |
| SCHEMBL8601626 | 0.85 | MAPT (0.47) | MMP2MAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8602533 | 0.84 | MMP2 (0.41) | MMP2MAPTSMN1; SMN2HTTRAB9A | |
| Trifluoroacetic Acid SCHEMBL8598750 | 0.84 | CDK4 (0.42) | MMP2SMN1; SMN2HTTALDH1A1MEN1 | |
| SCHEMBL8597525 | 0.83 | KMT2A (0.41) | MMP2MAPTSMN1; SMN2HTTNPC1 | |
| SCHEMBL8599397 | 0.82 | MEN1 (0.41) | MMP2MAPTSMN1; SMN2HTTSLC16A3 | |
| Hydrochloric Acid SCHEMBL8603024 | 0.82 | POLB (0.41) | MMP2MAPTSMN1; SMN2HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |