Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597593 | 0.88 | MMP2 (0.42) | CA12CA1CA2CA3CA4 | |
| SCHEMBL8599994 | 0.81 | MEN1 (0.40) | HTTPOLBSMN1; SMN2MMP2MEN1 | |
| SCHEMBL8596927 | 0.81 | MEN1 (0.43) | HTTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8597130 | 0.77 | MEN1 (0.38) | HTTALDH1A1POLBSMN1; SMN2MMP2 | |
| SCHEMBL8569083 | 0.77 | MMP2 (0.43) | HTTPOLBSMN1; SMN2MMP2MEN1 | |
| SCHEMBL8601626 | 0.76 | MAPT (0.47) | HTTALDH1A1SMN1; SMN2MMP2MEN1 | |
| SCHEMBL8601890 | 0.76 | TNF (0.46) | HTTSMN1; SMN2MMP2MEN1KMT2A | |
| SCHEMBL8603765 | 0.76 | TYK2 (0.46) | HTTSMN1; SMN2MEN1KMT2ARXFP1 | |
| SCHEMBL8651233 | 0.74 | KMT2A (0.39) | HTTPOLBSMN1; SMN2MMP2MEN1 | |
| SCHEMBL8597093 | 0.74 | MMP2 (0.42) | HTTPOLBSMN1; SMN2MMP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |