Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451039 | 0.82 | CES2 (0.34) | CES2CES1RAB9APOLBKMT2A | |
| SCHEMBL8299666 | 0.77 | NLRP3 (0.41) | CES2CES1RAB9APOLBKMT2A | |
| SCHEMBL8784070 | 0.76 | GAA (0.48) | CES2CES1RAB9AKMT2AMEN1 | |
| SCHEMBL1070351 | 0.73 | CA12 (0.61) | CES2CES1RAB9APOLBKMT2A | |
| SCHEMBL4478269 | 0.72 | NPC1 (0.50) | CES2CES1RAB9AKMT2AMEN1 | |
| Iodide SCHEMBL6190800 | 0.71 | CES2 (0.48) | CES2CES1POLBKMT2AMEN1 | |
| SCHEMBL17063994 | 0.71 | KMT2A (0.48) | RAB9APOLBKMT2ANPC1TDP1 | |
| SCHEMBL642257 | 0.70 | CES2 (0.46) | CES2CES1RAB9AKMT2AMEN1 | |
| SCHEMBL10441887 | 0.70 | CES2 (0.64) | CES2CES1RAB9APOLBKMT2A | |
| SCHEMBL14333527 | 0.69 | CES2 (0.50) | CES2CES1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821677-A1 | OXAZOLINE AND THIAZOLINE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| EP-0741714-A1 | ARTHROPODICIDAL 2-OXA AND THIA-ZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1996033180-A1 | OXAZOLINE AND THIAZOLINE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-10-24 | — | — | WO | disclosed |
| WO-1995019972-A1 | ARTHROPODICIDAL 2-OXA AND THIA-ZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-07-27 | — | — | WO | disclosed |