Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL31288570 | 0.85 | GRIK1 (0.47) | GRIK1GRIK2CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL175675 | 0.85 | — | — | |
| Acetic Acid SCHEMBL2164879 | 0.83 | GRIK1 (0.42) | GRIK1GRIK2CYP2C19SLC6A2SLC6A4 | |
| Fluoride SCHEMBL28175113 | 0.83 | ALDH1A1 (0.33) | GRIK1GRIK2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6531379 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL6288816 | 0.83 | ALDH1A1 (0.33) | GRIK1GRIK2ALDH1A1 | |
| Sulfuric Acid SCHEMBL4557083 | 0.82 | GRIK1 (0.33) | GRIK1GRIK2CYP2C19BLMGABBR2 | |
| Acetic Acid SCHEMBL17201408 | 0.76 | GABRR1 (0.46) | GABRR1GABBR2GABBR1GSRGABRP | |
| Isophthalic Acid SCHEMBL2829187 | 0.76 | ANPEP (0.44) | — | |
| SCHEMBL11256624 | 0.75 | CYP2D6 (0.57) | GRIK1GRIK2CYP2C19SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791941-B1 | NON-CHLORINATED CONCENTRATED ALL-IN-ONE ACID DETERGENT AND METHOD FOR USING THE SAME | DELAVAL HOLDING AB (SE) | 2013-03-13 | — | — | EP | claimed |
| US-7494963-B2 | Non-chlorinated concentrated all-in-one acid detergent and method for using the same | DELAVAL HOLDING AB (US) | 2009-02-24 | — | — | US | claimed |
| CN-101031634-A | Non-chlorinated concentrated all-in-one acid detergent and method for using the same | DELAVAL HOLDING AB (SE) | 2007-09-05 | — | — | CN | claimed |
| EP-1791941-A2 | NON-CHLORINATED CONCENTRATED ALL-IN-ONE ACID DETERGENT AND METHOD FOR USING THE SAME | DeLaval Holding AB (SE) | 2007-06-06 | — | — | EP | claimed |
| WO-2006020608-A2 | NON-CHLORINATED CONCENTRATED ALL-IN-ONE ACID DETERGENT AND METHOD FOR USING THE SAME | DELAVAL HOLDING AB (SE) | 2006-02-23 | — | — | WO | claimed |
| US-20060035808-A1 | Non-chlorinated concentrated all-in-one acid detergent and method for using the same | DELAVAL HOLDING AB (SE) | 2006-02-16 | — | — | US | claimed |
| US-10308891-B2 | Hydraulic fluid compositions | HOUGHTON TECHNICAL CORP. (US) | 2019-06-04 | — | — | US | disclosed |
| US-20160208193-A1 | HYDRAULIC FLUID COMPOSITIONS | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2016-07-21 | — | — | US | disclosed |
| US-8276663-B2 | Methods for reducing biological load in subterranean formations | HALLIBURTON ENERGY SERVICES INC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-20120073821-A1 | Methods for Reducing Biological Load in Subterranean Formations | HALLIBURTON ENERGY SERVICES, INC. | 2012-03-29 | — | — | US | disclosed |
| EP-2433998-A1 | Methods for reducing biological load in subterranean formations | Halliburton Energy Services, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| US-7600567-B2 | Desalination method | BP EXPLORATION OPERATING COMPANY LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| US-7455109-B2 | Water flooding method | BP EXPLORATION OPERATING COMPANY LIMITED (GB) | 2008-11-25 | — | — | US | disclosed |
| EP-1781898-B1 | WATER FLOODING METHOD | BP EXPLORATION OPERATING (GB) | 2008-10-08 | — | — | EP | disclosed |
| US-20080169098-A1 | Desalination Method | BP EXPLORATION OPERATING COMPANY LIMITED (GB) | 2008-07-17 | — | — | US | disclosed |
| US-20070246426-A1 | Water Flooding Method | BP EXPLORATION OPERATING COMPANY LIMITED (GB) | 2007-10-25 | — | — | US | disclosed |
| WO-2005119007-A1 | DESALINATION METHOD | BP EXPLORATION OPERATING COMPANY LIMITED (GB) | 2005-12-15 | — | — | WO | disclosed |