Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175675 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL6288816 | 0.84 | ALDH1A1 (0.33) | GRIK1GRIK2 | |
| Sulfuric Acid SCHEMBL5169847 | 0.84 | GRIK1 (0.39) | GRIK1GRIK2TP53 | |
| Hydrochloric Acid SCHEMBL6531379 | 0.84 | — | — | |
| Sulfuric Acid SCHEMBL28879549 | 0.84 | GRIK1 (0.39) | GRIK1GRIK2TP53 | |
| Fluoride SCHEMBL28175113 | 0.84 | ALDH1A1 (0.33) | GRIK1GRIK2 | |
| Acetic Acid SCHEMBL859882 | 0.82 | GRIK1 (0.40) | GRIK1GRIK2CYP2C19BLMGABBR2 | |
| Sulfuric Acid SCHEMBL14836674 | 0.81 | LMNA (0.32) | GRIK1GRIK2LMNASLC6A6CYP2C19 | |
| SCHEMBL14837155 | 0.76 | GRIK1 (0.36) | GRIK1GRIK2TP53 | |
| SCHEMBL355298 | 0.75 | LMNA (0.31) | LMNASLC6A6CYP2C19BLMGABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155855-A | INCLUDING FABRIC SUBSTANTIVE AGENT; STORAGE STABILITY | THE PROCTER & GAMBLE COMPANY (US) | 1979-05-22 | — | — | US | claimed |
| EP-0000406-A1 | Concentrated liquid fabric softener containing mixed active system | Procter & Gamble European Technical Center (BE) | 1979-01-24 | — | — | EP | claimed |
| EP-1922397-B1 | FABRIC CONDITIONING COMPOSITION | UNILEVER PLC (GB) | 2013-12-25 | — | — | EP | disclosed |
| US-20090036346-A1 | Fabric Conditioning Composition | Henkel IP & Holding GmbH (DE) | 2009-02-05 | — | — | US | disclosed |
| EP-1922397-A1 | FABRIC CONDITIONING COMPOSITION | Unilever Plc (GB) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007028495-A1 | FABRIC CONDITIONING COMPOSITION | UNILEVER PLC (GB) | 2007-03-15 | — | — | WO | disclosed |
| EP-0018039-B2 | FABRIC SOFTENING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |
| EP-0043622-B1 | FABRIC SOFTENING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-21 | — | — | EP | disclosed |
| EP-0018039-B1 | FABRIC SOFTENING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1984-03-07 | — | — | EP | disclosed |
| US-4386000-A | IMPROVED VISCOSITY AND STABILITY | THE PROCTER & GAMBLE COMPANY (US) | 1983-05-31 | — | — | US | disclosed |
| EP-0043622-A1 | Fabric softening composition | THE PROCTER & GAMBLE COMPANY (US) | 1982-01-13 | — | — | EP | disclosed |
| EP-0018039-A1 | Fabric softening composition | THE PROCTER & GAMBLE COMPANY (US) | 1980-10-29 | — | — | EP | disclosed |
| US-4155855-A | INCLUDING FABRIC SUBSTANTIVE AGENT; STORAGE STABILITY | THE PROCTER & GAMBLE COMPANY (US) | 1979-05-22 | — | — | US | disclosed |
| US-4149978-A | CATIONIC FABRIC SOFTENER AND A HYDROCARBON | THE PROCTER & GAMBLE COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
| EP-0000406-A1 | Concentrated liquid fabric softener containing mixed active system | Procter & Gamble European Technical Center (BE) | 1979-01-24 | — | — | EP | disclosed |