Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAN1B1 | Q9UKM7 | 10/20 | 0.51 |
| ▸ | MAN2A1 | Q16706 | 8/20 | 0.51 |
| ▸ | GBA1 | P04062 | 7/20 | 0.45 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.44 |
| ▸ | GLB1 | P16278 | 2/20 | 0.43 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21578193 | 0.70 | MAN1B1 (0.64) | MAN1B1MAN2A1GBA1MAN2B1GLB1 | |
| SCHEMBL21578194 | 0.70 | MAN1B1 (0.64) | MAN1B1MAN2A1GBA1MAN2B1GLB1 | |
| SCHEMBL20470481 | 0.70 | MAN1B1 (0.64) | MAN1B1MAN2A1GBA1MAN2B1GLB1 | |
| SCHEMBL21578196 | 0.70 | MAN1B1 (0.64) | MAN1B1MAN2A1GBA1MAN2B1GLB1 | |
| SCHEMBL5930460 | 0.70 | TYMP (0.40) | — | |
| SCHEMBL9025529 | 0.70 | TYMP (0.40) | — | |
| SCHEMBL31138990 | 0.70 | TYMP (0.42) | — | |
| SCHEMBL10515519 | 0.69 | KIF11 (0.43) | — | |
| SCHEMBL5443832 | 0.69 | TYMP (0.52) | — | |
| SCHEMBL10408396 | 0.69 | TYMP (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773239-A | ENZYME INHIBITORS FORMED BY MULTISTAGE REACTION FOR USE AS PRODRUGS | MOUNT SINAI HOSPITAL CORPORATION. (CA) | 1998-06-30 | — | — | US | disclosed |