Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601831 | 0.80 | KDM4E (0.34) | KDM4E | |
| SCHEMBL8630572 | 0.77 | CA12 (0.31) | — | |
| SCHEMBL8599625 | 0.76 | CA9 (0.36) | KDM4ETSHRKMT2ARAB9A | |
| SCHEMBL8597271 | 0.76 | ALDH1A1 (0.34) | TDP1 | |
| SCHEMBL8598387 | 0.75 | KDM4E (0.38) | KDM4EPOLBTDP1MEN1TSHR | |
| SCHEMBL8596770 | 0.75 | KMT2A (0.39) | KDM4EPOLBTDP1MEN1TSHR | |
| SCHEMBL8568327 | 0.74 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL3783321 | 0.73 | CA12 (0.43) | KDM4EPOLBTDP1MEN1TSHR | |
| SCHEMBL8600533 | 0.73 | TDP1 (0.38) | KDM4EPOLBTDP1MEN1TSHR | |
| SCHEMBL8602043 | 0.73 | KDM4E (0.38) | KDM4EPOLBTDP1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |