Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599145 | 0.76 | KDM4E (0.36) | TDP1 | |
| SCHEMBL8600107 | 0.76 | KDM4E (0.36) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8598691 | 0.75 | IMPDH2 (0.32) | ALDH1A1MAPTTDP1 | |
| SCHEMBL8597903 | 0.75 | GSK3A (0.41) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL8566844 | 0.74 | MEN1 (0.40) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL8598256 | 0.74 | HTT (0.37) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL17555458 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL8601697 | 0.73 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8599537 | 0.72 | KMT2A (0.36) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL8600759 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |