Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 6/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601717 | 0.80 | ALDH1A1 (0.36) | TDP1KDM4EMEN1KMT2AHTT | |
| SCHEMBL8598387 | 0.80 | KDM4E (0.38) | TDP1POLBKDM4EMEN1KMT2A | |
| SCHEMBL8600118 | 0.79 | MEN1 (0.33) | KDM4EMEN1KMT2AHTTLMNA | |
| SCHEMBL8599491 | 0.77 | HIF1A (0.39) | MEN1KMT2AHTTTSHRLMNA | |
| SCHEMBL8627058 | 0.77 | CA12 (0.35) | TDP1MEN1KMT2ATSHRNPY1R | |
| SCHEMBL8598070 | 0.76 | MEN1 (0.51) | TDP1POLBKDM4EMEN1KMT2A | |
| SCHEMBL8600588 | 0.74 | KDM4E (0.38) | TDP1POLBKDM4EMEN1KMT2A | |
| SCHEMBL8567904 | 0.74 | CA2 (0.39) | MEN1KMT2ANPY1RMAPTUSP2 | |
| SCHEMBL2683501 | 0.73 | NSD2 (0.38) | TDP1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL8599145 | 0.73 | KDM4E (0.36) | TDP1POLBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |