Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601373 | 0.82 | ALDH1A1 (0.46) | HPGDHTTALDH1A1GAAKDM4E | |
| SCHEMBL8568794 | 0.82 | HPGD (0.54) | HPGDHTTALDH1A1GAAGLA | |
| SCHEMBL8597620 | 0.80 | ESR1 (0.51) | HPGDALDH1A1GAAKDM4EPOLB | |
| SCHEMBL8598420 | 0.80 | HTT (0.59) | HPGDHTTALDH1A1GAAKDM4E | |
| SCHEMBL8596997 | 0.79 | HTT (0.51) | HPGDHTTALDH1A1GAAKDM4E | |
| SCHEMBL20460343 | 0.79 | P2RY12 (0.68) | HPGDHTTALDH1A1GAAKDM4E | |
| SCHEMBL8600541 | 0.79 | KDM4E (0.51) | HPGDHTTALDH1A1GAAKDM4E | |
| SCHEMBL8595814 | 0.77 | KMT2A (0.46) | HPGDHTTALDH1A1GAAKDM4E | |
| SCHEMBL8567699 | 0.76 | ALDH1A1 (0.48) | HTTALDH1A1POLBL3MBTL1MAPK1 | |
| SCHEMBL8568311 | 0.76 | ALOX15 (0.53) | HPGDALDH1A1POLBMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |