Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568311 | 0.88 | ALOX15 (0.53) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL8559145 | 0.85 | GRM2 (0.52) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL8561159 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL8569274 | 0.79 | MEN1 (0.43) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL8601373 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8568794 | 0.78 | HPGD (0.54) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL8566524 | 0.78 | MEN1 (0.53) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL28232869 | 0.78 | ALDH1A1 (0.66) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL8562941 | 0.77 | MAPT (0.57) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL8599321 | 0.76 | HPGD (0.48) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |