Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769748 | 0.92 | NPC1 (0.50) | DPP7NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL4445192 | 0.81 | NPC1 (0.51) | DPP7NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL13254845 | 0.81 | NPC1 (0.51) | DPP7NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL385345 | 0.81 | NPC1 (0.51) | DPP7NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL18241087 | 0.80 | L3MBTL1 (0.39) | NPC1RAB9ASMN1; SMN2POLBTDP1 | |
| SCHEMBL9864629 | 0.79 | POLB (0.49) | DPP7NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL4449748 | 0.79 | DPP7 (0.50) | DPP7NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL10757334 | 0.79 | NPC1 (0.50) | DPP7NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL4449743 | 0.79 | DPP7 (0.50) | DPP7NPC1RAB9ASMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL28414182 | 0.78 | L3MBTL3 (0.38) | NPC1RAB9ASMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020238179-A1 | PYRROLOPYRIMIDINE COMPOUND AS SELECTIVE JAK2 INHIBITOR, SYNTHESIS METHOD THEREFOR AND USE THEREOF | 上海勋和医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |
| US-5767286-A | REACTING A TETRAZOLINONE WITH A CARBAMOYL CHLORIDE IN THE PRESENCE OF 4-DIMETHYLAMINOPYRIDINE | NIHON BAYER AGROCHEM K. K. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0646577-B1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1998-06-03 | — | — | EP | disclosed |
| US-5747420-A | HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1998-05-05 | — | — | US | disclosed |
| EP-0711761-A1 | Tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0646577-A1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-3937824-A | COMPOSITIONS AND METHODS OF KILLING INSECTS AND ACARIDS USING ALKOXYIMINO CARBAMOYLOXY PHOSPHORUS COMPOUNDS | VELSICOL CHEMICAL CORPORATION (US) | 1976-02-10 | — | — | US | disclosed |