Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | C1R | P00736 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595032 | 0.82 | MAPT (0.40) | MEN1KMT2ATSHRHTTMAPT | |
| SCHEMBL8596304 | 0.82 | MAPT (0.38) | MEN1KMT2ATSHRHTTC1R | |
| SCHEMBL8599003 | 0.80 | KDM4E (0.37) | MEN1KMT2AHTTMAPTALDH1A1 | |
| SCHEMBL8625911 | 0.80 | MAPT (0.35) | MEN1KMT2AMAPTMGMTALDH1A1 | |
| SCHEMBL8596283 | 0.80 | MEN1 (0.37) | ESR1MEN1KMT2ATSHRHTT | |
| SCHEMBL8599095 | 0.79 | ALDH1A1 (0.37) | MEN1KMT2ATSHRHTTMAPT | |
| SCHEMBL8562557 | 0.78 | ALDH1A1 (0.41) | MEN1KMT2ATSHRHTTMAPT | |
| SCHEMBL8601173 | 0.77 | ALDH1A1 (0.42) | ESR1MEN1KMT2ATSHRHTT | |
| SCHEMBL8559187 | 0.76 | KDM4E (0.40) | MEN1KMT2ATSHRHTTMAPT | |
| SCHEMBL8562624 | 0.75 | TXNRD1 (0.50) | HTTMAPTMGMTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |