Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600276 | 0.82 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL8598395 | 0.80 | ALDH1A1 (0.40) | ALDH1A1HPGDTP53TSHRHSD17B10 | |
| SCHEMBL8921743 | 0.80 | TP53 (0.44) | ALDH1A1HPGDTP53KDM4EMEN1 | |
| SCHEMBL8563341 | 0.79 | MAPT (0.49) | ALDH1A1HPGDTP53TSHRHSD17B10 | |
| SCHEMBL8599095 | 0.79 | ALDH1A1 (0.37) | ALDH1A1HPGDTP53TSHRHSD17B10 | |
| SCHEMBL8561968 | 0.78 | MAP2K3 (0.49) | ALDH1A1HPGDTP53TSHRHSD17B10 | |
| SCHEMBL8599396 | 0.77 | ESR1 (0.38) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL8565819 | 0.76 | HSD17B10 (0.49) | ALDH1A1HPGDTP53TSHRHSD17B10 | |
| SCHEMBL8567818 | 0.75 | HPGD (0.40) | HPGDKDM4EMEN1KMT2ALMNA | |
| SCHEMBL8597709 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |