Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598610 | 0.97 | KMT2A (0.57) | KMT2AALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL15855770 | 0.90 | AKR1C3 (0.48) | KMT2AALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL10534461 | 0.87 | KDM4E (0.54) | KMT2AALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL21246147 | 0.86 | CYP1A2 (0.53) | KMT2AALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL18017191 | 0.84 | KMT2A (0.53) | KMT2AALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL6302198 | 0.84 | ALDH1A1 (0.61) | KMT2AALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL31139593 | 0.83 | KMT2A (0.56) | KMT2AALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL1666684 | 0.81 | KMT2A (0.50) | KMT2AALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL15293703 | 0.80 | CDC25B (0.67) | KMT2AALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL31144076 | 0.80 | CDC25B (0.67) | KMT2AALDH1A1KDM4ECYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707557-A | Photochromic 3H-naphthopyrans | OPTISCHE WERKE G. RODENSTOCK (DE) | 1998-01-13 | — | — | US | disclosed |