Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601859 | 0.86 | DCTPP1 (0.54) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL8602071 | 0.81 | MAPT (0.46) | ALDH1A1MAPTIRAK4GAASMN1; SMN2 | |
| SCHEMBL13990316 | 0.81 | IRAK4 (0.49) | ALDH1A1MAPTIRAK4GAASMN1; SMN2 | |
| SCHEMBL8602825 | 0.79 | TSHR (0.52) | ALDH1A1MAPTIRAK4 | |
| SCHEMBL8601368 | 0.78 | MAPT (0.46) | ALDH1A1MAPTIRAK4GAASMN1; SMN2 | |
| SCHEMBL8668207 | 0.78 | IRAK4 (0.45) | ALDH1A1MAPTIRAK4GAASMN1; SMN2 | |
| SCHEMBL8602363 | 0.78 | PIK3C2B (0.52) | ALDH1A1CYP1A2MAPTLMNAPOLB | |
| SCHEMBL8565463 | 0.77 | IRAK4 (0.48) | IRAK4 | |
| SCHEMBL8602584 | 0.76 | IRAK4 (0.44) | MAPTIRAK4 | |
| SCHEMBL8596516 | 0.76 | IRAK4 (0.49) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |