Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28055631 | 0.73 | KDM4E (0.32) | LMNATP53NFKB1THPOGMNN | |
| SCHEMBL18639953 | 0.72 | SRD5A2 (0.39) | CYP2C19RAB9A | |
| SCHEMBL2761082 | 0.71 | HTR3E (0.31) | — | |
| SCHEMBL1681910 | 0.70 | EPHX2 (0.33) | NPC1RAB9A | |
| SCHEMBL9179865 | 0.69 | KDM4E (0.32) | LMNATP53NFKB1THPOGMNN | |
| Bicarbonate SCHEMBL10352400 | 0.67 | TFPI2 (0.50) | MAPK1LMNATP53NFKB1CYP2C19 | |
| Bicarbonate SCHEMBL2914629 | 0.67 | TFPI2 (0.50) | MAPK1LMNATP53NFKB1CYP2C19 | |
| SCHEMBL6232445 | 0.65 | KMT2A (0.46) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5821158 | 0.65 | KMT2A (0.46) | NPC1RAB9ASMN1; SMN2 | |
| Methyl Alcohol SCHEMBL8603255 | 0.65 | LMNA (0.33) | LMNATP53NFKB1THPOGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808108-A | DENTAL COMPOSITES | CURATORS OF THE UNIVERISITY OF MISSOURI | 1998-09-15 | — | — | US | disclosed |