Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871113 | 0.81 | IDH1 (0.51) | PKMIDH1CALM1CYP2C9KDM4A | |
| SCHEMBL4387604 | 0.78 | NR4A2 (0.40) | PKMKDM4EMEN1MAPTKMT2A | |
| SCHEMBL28175236 | 0.78 | NR4A2 (0.40) | PKMKDM4EMEN1MAPTKMT2A | |
| SCHEMBL4389974 | 0.78 | RECQL (0.52) | PKMKDM4EMEN1MAPTKMT2A | |
| SCHEMBL5519979 | 0.78 | LOXL2 (0.52) | NR4A2SOS2ROCK1 | |
| SCHEMBL30471785 | 0.78 | NR4A2 (0.40) | PKMKDM4EMEN1MAPTKMT2A | |
| SCHEMBL29878333 | 0.77 | CYP3A4 (0.58) | PKMCYP3A4CYP2C19HIF1ALMNA | |
| SCHEMBL3898712 | 0.77 | CYP3A4 (0.58) | PKMCYP3A4CYP2C19HIF1ALMNA | |
| SCHEMBL5531943 | 0.77 | NR4A2 (0.39) | PKMCYP2C19MEN1MAPTKMT2A | |
| SCHEMBL27956165 | 0.76 | CA2 (0.50) | KDM4EHIF1AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |