Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | FERMT2 | Q96AC1 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4389974 | 0.82 | RECQL (0.52) | NR4A2SOS2CYP1A2CCR1PKM | |
| SCHEMBL30471785 | 0.82 | NR4A2 (0.40) | NR4A2SOS2CYP1A2CCR1PKM | |
| SCHEMBL4387604 | 0.82 | NR4A2 (0.40) | NR4A2SOS2CYP1A2CCR1PKM | |
| SCHEMBL5519979 | 0.82 | LOXL2 (0.52) | NR4A2SOS2CYP1A2CCR1FERMT2 | |
| SCHEMBL5531943 | 0.81 | NR4A2 (0.39) | NR4A2SOS2CYP1A2CCR1PKM | |
| SCHEMBL19877353 | 0.79 | NR4A2 (0.38) | NR4A2SOS2CYP1A2CCR1PKM | |
| SCHEMBL27591763 | 0.79 | NR4A2 (0.38) | NR4A2SOS2CYP1A2CCR1PKM | |
| SCHEMBL8602761 | 0.78 | MAOA (0.46) | NR4A2SOS2CYP1A2CCR1PKM | |
| SCHEMBL8599580 | 0.78 | PKM (0.47) | NR4A2SOS2PKMMAPTKMT2A | |
| SCHEMBL11729426 | 0.77 | SMYD3 (0.41) | CYP1A2CCR1PKMSMYD3FERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107438598-A | QUINAZOLINE AND QUINOLINE COMPOUNDS AND USES THEREOF | 米伦纽姆医药公司 | 2017-12-05 | — | — | CN | disclosed |