SCHEMBL8599640

SCHEMBL8599640

CC(=O)Nc1ccc(C#CC(=O)O)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.75
MEN1 O00255 5/20 0.75
SMN1; SMN2 Q16637 4/20 0.75
ALDH1A1 P00352 4/20 0.75
RAB9A P51151 4/20 0.75
KDM4E B2RXH2 1/20 0.75
HPGD P15428 1/20 0.75
CYP2C19 P33261 1/20 0.75
L3MBTL1 Q9Y468 2/20 0.53
HTT P42858 1/20 0.53
NAPRT Q6XQN6 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAPT P10636 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
CA12 O43570 1/20 0.52
BRD4 O60885 1/20 0.52
NR1I2 O75469 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
MB P02144 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8595810 0.98 KMT2A (0.72) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
Guanidine SCHEMBL10363125 0.92 KMT2A (0.64) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL2231385 0.83 RAB9A (0.85) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
Potassium Ion SCHEMBL8595807 0.82 KMT2A (0.70) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL14418989 0.81 APP (0.57) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL10191870 0.81 KMT2A (0.81) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL9629232 0.79 FFAR1 (0.50) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL20717672 0.79 RAB9A (0.70) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL861674 0.77 SMN1; SMN2 (0.84) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL3053096 0.76 KMT2A (0.72) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0452853-B1 Heat-developable color-sensitive material FUJI PHOTO FILM CO LTD (JP) 1998-01-28 EP disclosed
EP-0386761-B1 Heat developable color photosensitive material FUJI PHOTO FILM CO LTD (JP) 1997-06-04 EP disclosed
EP-0378174-B1 Light-sensitive element for the diffusion transfer process FUJI PHOTO FILM CO LTD (JP) 1997-04-09 EP disclosed
EP-0394943-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1996-11-20 EP disclosed
EP-0385496-B1 Color light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1996-07-31 EP disclosed
EP-0426112-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-02-28 EP disclosed
EP-0334362-B1 Heat developable color light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1995-09-20 EP disclosed
EP-0351860-B1 Color light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1995-07-12 EP disclosed
US-5427901-A Has spectral sensitivity characteristics in at least one silver halide emulsion layer which provides superior color separation from other layers having a sensitivity in the infrared region FUJI PHOTO FILM CO., LTD. (JP) 1995-06-27 US disclosed
EP-0357040-B1 Heat-developable color photographic material and method for forming image using same FUJI PHOTO FILM CO LTD (JP) 1995-05-10 EP disclosed
US-4851327-A THIN SOLID METAL FILM FUJI PHOTO FILM CO., LTD. (JP) 1989-07-25 US disclosed
US-4839272-A IMPROVED MAGENTA DYE-PROVIDING SUBSTANCES FUJI PHOTO FILM CO., LTD. (JP) 1989-06-13 US disclosed
US-4820622-A RELEASING DIFFUSIBLE DYE IN ALKALINE SYSTEM AFTER HALIDE REDUCTION FUJI PHOTO FILM CO., LTD. (JP) 1989-04-11 US disclosed
US-4782004-A PHENOLIC SULFONAMIDE OR POLYMER WITH PHENOL AND/OR SULFONAMIDE GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1988-11-01 US disclosed
EP-0177033-B1 HEAT-DEVELOPABLE LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1988-08-24 EP disclosed
US-4764458-A CONTAINING ORGANIC SILVER SALT OF UNSATURATED AROMATIC CARBOXYLATE FUJI PHOTO FILM CO., LTD. (JP) 1988-08-16 US disclosed
EP-0253390-A2 Photographic support and color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
US-4657848-A STORAGE STABILITY, ANTIFOGGING, HIGH DENSITY IMAGE FUJI PHOTO FILM CO., LTD. (JP) 1987-04-14 US disclosed
EP-0198356-A1 Heat developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-10-22 EP disclosed
EP-0177033-A2 Heat-developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-04-09 EP disclosed