Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | MB | P02144 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599640 | 0.82 | KMT2A (0.75) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8595810 | 0.81 | KMT2A (0.72) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL10191870 | 0.78 | KMT2A (0.81) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| Silver SCHEMBL10352457 | 0.77 | NPSR1 (0.39) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL10352458 | 0.77 | NPSR1 (0.39) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL2231385 | 0.77 | RAB9A (0.85) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| Guanidine SCHEMBL10363125 | 0.76 | KMT2A (0.64) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL861674 | 0.74 | SMN1; SMN2 (0.84) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL3053096 | 0.74 | KMT2A (0.72) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL16346196 | 0.74 | KMT2A (0.72) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452853-B1 | Heat-developable color-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5427901-A | Has spectral sensitivity characteristics in at least one silver halide emulsion layer which provides superior color separation from other layers having a sensitivity in the infrared region | FUJI PHOTO FILM CO., LTD. (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0452853-A1 | Heat-developable color-sensitive material | Fuji Photo Film Co., Ltd. (JP) | 1991-10-23 | — | — | EP | disclosed |
| US-4774162-A | POLYMERIC MORDANTS, MULTILAYERS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |