Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15058851 | 0.84 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4958816 | 0.83 | TDP1 (0.39) | CA1CA2TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL1257360 | 0.83 | LMNA (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2013038 | 0.82 | LMNA (0.55) | ALDH1A1TSHRSLC6A2TDP1SLC6A3 | |
| SCHEMBL5153060 | 0.79 | ESR1 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4640184 | 0.77 | TAS1R3 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13892423 | 0.75 | LMNA (0.50) | ALDH1A1PRKCATSHRSLC6A2TDP1 | |
| SCHEMBL16114298 | 0.74 | LMNA (0.46) | ALDH1A1TSHRESR1SLC6A2SLC6A3 | |
| SCHEMBL8388924 | 0.74 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL128505 | 0.74 | CA12 (0.46) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795562-A | BIODEGRADABLE POLYMER AS CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | NYCOMED IMAGING AS (NO) | 1998-08-18 | — | — | US | disclosed |