Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601051 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EPOLBTSHR | |
| SCHEMBL8596253 | 0.78 | CYP19A1 (0.40) | ALDH1A1POLBMAPK1LMNAMAPT | |
| SCHEMBL8600585 | 0.77 | ESR1 (0.54) | ALDH1A1HSD17B10KDM4EPOLBTSHR | |
| SCHEMBL8601053 | 0.77 | ESR1 (0.54) | ALDH1A1HSD17B10KDM4EPOLBTSHR | |
| SCHEMBL8626079 | 0.76 | CA2 (0.37) | TSHRMAPK1MAPTNPC1RAB9A | |
| SCHEMBL8565798 | 0.75 | RAB9A (0.55) | ALDH1A1KDM4EPOLBTSHRCYP3A4 | |
| SCHEMBL6657026 | 0.74 | TSHR (0.60) | ALDH1A1HSD17B10KDM4EPOLBTSHR | |
| SCHEMBL8598969 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KDM4EPOLBTSHR | |
| SCHEMBL8599426 | 0.74 | ESR1 (0.48) | ALDH1A1HSD17B10KDM4EPOLBTSHR | |
| SCHEMBL6655348 | 0.73 | ALDH1A1 (0.61) | ALDH1A1HSD17B10KDM4EPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |