Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598193 | 0.94 | ELANE (0.39) | CUL4AELANEHTTRECQLALDH1A1 | |
| SCHEMBL8598539 | 0.92 | ELANE (0.38) | ELANEHTTRECQLALDH1A1L3MBTL1 | |
| SCHEMBL8601864 | 0.90 | CUL4A (0.44) | CUL4AELANE | |
| SCHEMBL8599287 | 0.84 | L3MBTL1 (0.48) | HTTRECQLALDH1A1L3MBTL1TDP1 | |
| SCHEMBL8603030 | 0.84 | CUL4A (0.40) | CUL4AHTTALDH1A1LMNANPSR1 | |
| SCHEMBL8602400 | 0.81 | DHODH (0.32) | MAPT | |
| SCHEMBL8599225 | 0.81 | PPOX (0.40) | HTTRECQLALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL8599624 | 0.81 | CUL4A (0.31) | CUL4AMAPT | |
| SCHEMBL8598105 | 0.81 | ELANE (0.35) | ELANE | |
| SCHEMBL9814276 | 0.79 | CUL4A (0.44) | CUL4AALDH1A1TDP1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |